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How does Qsiva work?
Qsiva contains two active ingredients, phentermine and topiramate. Phentermine is a commonly establish weight loss drug. Until about a decade ago, when concerns were raised about its long-term health impact and whether it is addictive. Phentermine is no longer prescribe in the UK, but there are some specialist weight loss clinics that prescribe this drug for short-term use. Phentermine remains the most commonly prescribed weight loss drug in the United States.
Topiramate was ratify in 1996 as a treatment for epilepsy and, more recently, as a treatment for the prevention of migraine.
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Topiramate acts through GABA receptors in the brain to increase feelings of satiety and fullness. Phentermine stimulates the release of the neurotransmitter norepinephrine, which reduces appetite. The combination of topiramate and phentermine appears to increase the window of effectiveness of topiramate.
Is Qsiva effective?
Qsiva has gone through two different phases. The FDA requires III of the clinical trials and the results of the studies show that it is an effective weight loss aid in obese patients. where can i buy qsymia online?
In the EQUIP studies, which lasted 56 weeks and included 1,267 obese patients, the data showed that:
On average, patients who took the drug at full strength lost 14.7% of their body weight. Compared with 2.5% for those who received placebo over the 56-week period
84% of patients on the highest dose lost 5% or more of their total body weight, and 59% on the lowest dose achieved the same results, compared to only 26% in the placebo group who achieved the same result.
The average weight loss for the high dose group was 37 pounds, 18 pounds for the low dose group and 6 pounds for the placebo group.
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In the CONQUER studies, involving 2,487 patients with comorbidities such as hypertension, type 2 diabetes and high cholesterol, the results were as follows over a 56-week period:
Patients lost 13.2% of their total body weight with the high dose, 10.5% with the low dose and 2.4% with the placebo.
Eighty-five percent of patients on the high dose and 75% on the low dose lost 5% or more of their body weight, compared with 26% in the placebo group.
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As with any medicine, Qsiva appears to have some side effects in some patients. The most common are dry mouth, pins and needles, constipation, taste disturbances and insomnia. The drug does not appear to cause mood problems, depression or suicidal ideation.
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There were concerns about previously announce phentermine side effects. Increased blood pressure and topiramate, i.e. cognitive problems and depression. However, both drugs are present in Qsiva at very low doses and there is no indication in clinical trial data that the drug causes any of these or other serious side effects.
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The Online Clinic has always averse the prescription of phentermine alone, but if this new extended-release formulation in combination with topiramate is found to be safe and effective, then we will seriously consider prescribing it once the European Medicines Agency and the European Medicines Agency approve the drug. MHRA. where to buy qsymia online
When will Qsiva be available?
Qsymia is available in the United States through some doctors but may be online. If a European licence is reaudition for, we expect Qsiva to be available in 2015 in the EU. where to buy qsymia diet pills online
Register your interest in Qsiva
Although we cannot prescribe Qsiva at the moment. But if you register for a weight loss consultation now and agree to be on our mailing list, we will notify you as soon as Qsiva becomes available. Buy Qsymia (phentermine topiramate).